Article

Extraordinary peptide-binding mode of a songbird MHC class-I molecule suggests mechanism to counter pathogen immune evasion

2023-03-13

Abstract excerpt

Long-distance migratory animals such as birds and bats have evolved to withstand selection imposed by pathogens across the globe, and pathogen richness is known to be particularly high in tropical regions. Immune genes, so-called Major Histocompatibility Complex (MHC) genes, are highly duplicated in songbirds compared to other vertebrates, and this high MHC diversity has been hypothesised to result in a unique ada...

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Literature Corpus work: 0a3d4469-6c53-5732-9843-02ae10b93086
DOI: 10.1101/2023.03.13.532050

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Extraordinary peptide-binding mode of a songbird MHC class-I molecule suggests mechanism to counter pathogen immune evasionDOI 10.1101/2023.03.13.532050Read

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