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Article

Evolution by selection, recombination, and gene duplication in MHC class I genes of two Rhacophoridae species.

BMC evolutionary biology - 5 Jun 2013

Zhao Mian, Wang Yongzhen, Shen Hang, Li Chenliang, Chen Cheng, Luo Zhenhua, Wu Hua

Abstract excerpt

BACKGROUND: Comparison of major histocompatibility complex (MHC) genes across vertebrate species can reveal molecular mechanisms underlying the evolution of adaptive immunity-related proteins. As the first terrestrial tetrapods, amphibians deserve special attention because of their exposure to probably increased spectrum of microorganisms compared with ancestral aquatic fishes. Knowledge regarding the...

Topics

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Evolution, Molecular
Exons
Gene Duplication
Genes, MHC Class I
Ranidae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Recombination, Genetic

Selection, Genetic

Sequence Alignment

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Identifiers

PMID: 23734729
DOI: 10.1186/1471-2148-13-113
PMCID: PMC3684511

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