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Article

MHC class II DR classification based on antigen-binding groove natural selection.

Biochemical and biophysical research communications - 24 Jul 2009

Takeshima Shin-nosuke, Sarai Akinori, Sarai Yoshinori, Saitou Naruya, Aida Yoko

Abstract excerpt

Major histocompatibility complex (MHC) genes are highly polymorphic and play key roles in immune susceptibility and resistance to pathogens. While the immunological and structural functions of several human and murine alleles have been analyzed, little is known about the MHC molecules of other animals. Here, we could classify five mammalian species into three groups (human, cow and dog, and cat and pig) on the...

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Identifiers

PMID: 19422791
DOI: 10.1016/j.bbrc.2009.04.142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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