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A family of unusual immunoglobulin superfamily genes in an invertebrate histocompatibility complex

26 Sept 2022

Abstract excerpt

Most colonial marine invertebrates are capable of allorecognition, the ability to distinguish between themselves and conspecifics. One long-standing question is whether invertebrate allorecognition genes are homologous to vertebrate histocompatibility genes. In the cnidarian Hydractinia symbiolongicarpus, allorecognition is controlled by at least two genes, Allorecognition 1 ( Alr1 ) and Allorecognition 2 ( Alr2...

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PMID: 36161920
DOI: 10.1073/pnas.2207374119

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