Article

The mechanistic role of long non-coding RNAs in advanced prostate cancer response to therapy

2020-01-01

Abstract excerpt

Prostate cancer is one of the most common malignancies and the fifth leading cause of cancer related deaths in males, worldwide. It is commonly treated using androgen deprivation therapy (ADT), but around 25% develop ADT resistance and are called Castration-Resistant Prostate Cancers (CRPCs). Therapies currently used for CRPC treatment include: the new generation anti-androgen enzalutamide, the taxane cabazitaxel...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 09e54519-4215-5949-8e7b-4ce471627096
DOI: 10.21954/ou.ro.000111da

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The mechanistic role of long non-coding RNAs in advanced prostate cancer response to therapyDOI 10.21954/ou.ro.000111daRead

The long noncoding RNA HORAS 5 mediates castration‐resistant prostate cancer survival by activating the androgen receptor transcriptional programSemantic proximity Read

Novel hormone therapies for advanced prostate cancer: Understanding and countering drug resistanceSemantic proximity Read

Circular RNAs are differentially expressed in prostate cancer and are potentially associated with resistance to enzalutamideSemantic proximity Read

Identification of genes required for enzalutamide resistance in castration-resistant prostate cancer cells <i>in vitro</i>Semantic proximity Read

Current Insights into Long Non-Coding RNAs (LncRNAs) in Prostate CancerSemantic proximity Read

Dissecting major signaling pathways in prostate cancer development and progression: Mechanisms and novel therapeutic targets.Semantic proximity Read

Androgen Receptor Signaling Pathway in Prostate Cancer: From Genetics to Clinical ApplicationsSemantic proximity Read

Durable Response of Enzalutamide-resistant Prostate Cancer to Supraphysiological Testosterone Is Associated with a Multifaceted Growth Suppression and Impaired DNA Damage Response Transcriptomic Program in Patient-derived XenograftsSemantic proximity Read

Transcriptome Sequencing Reveals PCAT5 as a Novel ERG-Regulated Long Noncoding RNA in Prostate Cancer.Semantic proximity Read

Understanding the function of Pax5 in development of docetaxel-resistant neuroendocrine-like prostate cancersSemantic proximity Read

GG-NER's role in androgen receptor signaling inhibitor response for advanced prostate cancer.Semantic proximity Read

Comparative RNA-seq analysis reveals potential mechanisms mediating the conversion to androgen independence in an LNCaP progression cell model.Semantic proximity Read