Article

Forecasting multi-trait resistance evolution under antibiotic stress

2025-10-17

Abstract excerpt

Many bacteria rely on efflux pumps to survive antibiotic stress, and exposure to antibiotics often leads to mutations in pump genes or their regulators that increase pump expression. Predicting the spectrum of these mutations is important for designing effective antibiotic treatments, but the underlying regulatory networks are large and complex, making them difficult to map experimentally. To address this challeng...

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Literature Corpus work: 09ced3f5-7556-504b-93f0-b15fe7116a47
DOI: 10.1101/2025.10.17.683023

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