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Article

Inhibition of CPT1a as a Prognostic Marker can Synergistically Enhance the Antileukemic Activity of ABT199

2021-03-16

Abstract excerpt

<title>Abstract</title> <p>Background Fatty acid oxidation (FAO) provides an important source of energy to promote the growth of leukemia cells. Carnitine palmitoyltransferase 1a(CPT1a), a rate-limiting enzyme of the essential step of FAO, can facilitate cancer metabolic adaptation. Previous reports demonstrated that CPT1a acts as a potential molecular target in solid tumors and hematologic disease. However, no...

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Literature Corpus work
09cc8bf9-58e5-58f6-b36c-d09cc6ad88a9
DOI
10.21203/rs.3.rs-255509/v2
Open publication

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Inhibition of CPT1a as a Prognostic Marker can Synergistically Enhance the Antileukemic Activity of ABT199DOI 10.21203/rs.3.rs-255509/v2
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