Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High Expression of CPT1A Predicts Adverse Outcomes: A Potential Therapeutic Target for Acute Myeloid Leukemia

22 Nov 2016

Abstract excerpt

Carnitine palmitoyl transferase 1A ( CPT1A ) protein catalyzes the rate-limiting step of Fatty-acid oxidation ( FAO ) pathway, which can promote cell proliferation and suppress apoptosis. Targeting CPT1A has shown remarkable anti-leukemia activity. But, its prognostic value remains unclear in Acute Myeloid Leukemia (AML). In two independent cohorts of cytogenetically normal AML (CN-AML) patients, compared to low...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Cancer, Lipids, and Metabolism
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27916548
DOI: 10.1016/j.ebiom.2016.11.025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High Expression of CPT1A Predicts Adverse Outcomes: A Potential Therapeutic Target for Acute Myeloid LeukemiaPMID 27916548Read ↗

Inhibition of CPT1a as a Prognostic Marker can Synergistically Enhance the Antileukemic Activity of ABT199Semantic proximity Read ↗

Identification of LPCAT1 expression as a potential prognostic biomarker guiding treatment choice in acute myeloid leukemiaSemantic proximity Read ↗

The Multi-Omic Prognostic Model of Oxidative Stress-Related Genes in Acute Myeloid LeukemiaSemantic proximity Read ↗

A Novel Fatty Acid Metabolism-Associated Risk Model for Prognosis Prediction in Acute Myeloid LeukaemiaSemantic proximity Read ↗

OXPHOS mediators in acute myeloid leukemia patients: Prognostic biomarkers and therapeutic targets for personalized medicine.Semantic proximity Read ↗

Long noncoding RNAs: A novel insight in the leukemogenesis and drug resistance in acute myeloid leukemiaSemantic proximity Read ↗

Development and validation of a novel survival model for acute myeloid leukemia based on autophagy-related genesSemantic proximity Read ↗

Identification of a Mitochondria-Related Gene Signature to Predict the Prognosis in AMLSemantic proximity Read ↗

A Comprehensive Metabolism-Related Gene Signature Predicts the Survival of Patients with Acute Myeloid LeukemiaSemantic proximity Read ↗

PLA2G4A Is a Potential Biomarker Predicting Shorter Overall Survival in Patients with Non-M3/ NPM1 Wildtype Acute Myeloid LeukemiaSemantic proximity Read ↗

Integrated proteogenomic and metabolomic profiling of acute myeloid leukemias to identify molecular subtypes and associated therapy targets.Semantic proximity Read ↗

Construction of a novel prognostic risk model based on m6A-related miRNAs for acute myeloid leukemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.