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Article

Potential role of autophagy induced by FLT3-ITD and acid ceramidase in acute myeloid leukemia chemo-resistance: new insights.

Cell communication and signaling : CCS - 31 Oct 2022

Zalpoor Hamidreza, Bakhtiyari Maryam, Akbari Abdullatif, Aziziyan Fatemeh, Shapourian Hooriyeh, Liaghat Mahsa, Zare-Badie Zahra, Yahyazadeh Sheida, Tarhriz Vahideh, Ganjalikhani-Hakemi Mazdak

Abstract excerpt

Acute myeloid leukemia (AML) is a type of leukemia with a poor prognosis and survival characterized by abnormal cell proliferation and differentiation. Despite advances in treatment, AML still has a low complete remission rate, particularly in elderly patients, and recurrences are frequently seen even after complete remissions. The major challenge in treating AML is the resistance of leukemia cells to...

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PMID: 36316776
DOI: 10.1186/s12964-022-00956-7
PMCID: PMC9620650

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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