Article

Structural insights into the heterotrimeric alternatively spliced P2X7 receptors

2023-05-30

Abstract excerpt

<h4>Summary</h4> AlphaFold2-Multimer was used to generate structures of the heterotrimeric P2X7 receptors composed of wild-type P2X7A subunits and alternatively spliced subunits (P2X7B, P2X7E, P2X7J, and P2X7L) that have been confirmed in humans. The study supports laboratory research by providing insight into the structure and flexibility of the heterotrimeric alternatively spliced receptors in a simulated envir...

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Literature Corpus work: 09cc6d54-e621-5ccf-8693-ccfd8be42b50
DOI: 10.1101/2023.05.30.542804

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