Article

Integrated single-cell and bulk RNA sequencing identifies SERPING1 as an immune infiltration regulator and therapeutic target in Triple-negative breast cancer

2025-08-27

Abstract excerpt

<title>Abstract</title> <p>Background Triple-negative breast cancer (TNBC) is an aggressive malignancy that lacks effective treatment. Immune infiltration plays an important role in activating anti-tumor responses. This study aims to identify regulators of immune infiltration and potential therapeutic targets for TNBC. Methods Single-cell RNA sequencing (scRNA-seq) and bulk RNA sequencing data were obtained from...

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Literature Corpus work: 4ffc8310-8094-56aa-a69f-f057c6c90b1c
DOI: 10.21203/rs.3.rs-7064973/v1

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