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Azacytidine restores T cell function in AML by modulating DNA methylation

2026-06-17

Abstract excerpt

AML is an aggressive blood cancer associated with poor clinical outcomes. Chemotherapy remains the standard of treatment, but unfortunately relapse is very common, highlighting the need for alternative therapies. T cell dysfunction and exhaustion are prominent in AML and may represent a barrier to effective immunotherapy yet remains poorly studied in AML. DNA methylation is a major driver of T cell exhaustion and...

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Literature Corpus work
0994dcca-26ce-50ef-b650-a4ca1fa7a09b
DOI
10.64898/2026.06.14.732148
Open publication

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Azacytidine restores T cell function in AML by modulating DNA methylationDOI 10.64898/2026.06.14.732148
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