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Article

Epigenetic Therapy in Acute Myeloid Leukemia: Current and Future Directions.

Seminars in hematology - 1 Jul 2015

Kim Tae Kon, Gore Steven D, Zeidan Amer M

Abstract excerpt

Epigenetic modifications affect gene expression without changes in the actual DNA sequence. Two of the most important mechanisms include DNA methylation and histone tail modifications (especially acetylation and methylation). Epigenetic modulation is a part of normal physiologic development; its dysregulation is an important mechanism of pathogenesis of some cancers, including acute myeloid leukemia (AML)....

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Share to DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26111464
DOI: 10.1053/j.seminhematol.2015.04.003
PMCID: PMC5785931

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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