Article

Scalable metabolic pathway analysis

2020-08-01

Abstract excerpt

The scope of application of genome-scale constraint-based models (CBMs) of metabolic networks rapidly expands toward multicellular systems. However, comprehensive analysis of CBMs through metabolic pathway analysis remains a major computational challenge because pathway numbers grow combinatorially with model sizes. Here, we define the minimal pathways (MPs) of a metabolic (sub)network as a subset of its elementar...

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Literature Corpus work: 098fa56d-bc29-5c49-b40c-451d2f7ab9d2
DOI: 10.1101/2020.07.31.230177

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