Article
More than just a gut feeling: constraint-based genome-scale metabolic models for predicting functions of human intestinal microbes.
Microbiome - 14 Jul 2017
van der Ark Kees C H, van Heck Ruben G A, Martins Dos Santos Vitor A P, Belzer Clara, de Vos Willem M
Abstract excerpt
The human gut is colonized with a myriad of microbes, with substantial interpersonal variation. This complex ecosystem is an integral part of the gastrointestinal tract and plays a major role in the maintenance of homeostasis. Its dysfunction has been correlated to a wide array of diseases, but the understanding of causal mechanisms is hampered by the limited amount of cultured microbes, poor understanding of...
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