Article

Complete genome-derived metabolic interactions reveal impact of gut ecology on human health

2026-03-26

Abstract excerpt

Metabolic interactions govern gut microbiome assembly, yet functional rules remain obscured by genomic incompleteness and fragmentation. Here, we leverage 1,150 complete genomes to construct genome-scale metabolic models, demonstrating that draft genomes introduce systemic artifacts missing critical transport functions. We observe that metabolic interactions are intrinsically driven by genomic traits and niche spe...

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Literature Corpus work: 077bf6ca-4503-57a6-b5fc-e33c06cea345
DOI: 10.64898/2026.03.25.714329

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