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Article

Network reduction methods for genome-scale metabolic models.

Cellular and molecular life sciences : CMLS - 1 Feb 2020

Singh Dipali, Lercher Martin J

Abstract excerpt

Genome-scale metabolic models (GSMs) provide a comprehensive representation of cellular metabolism. GSMs provide a mechanistic link between cellular genotypes and metabolic phenotypes, and are thus widely used to analyze metabolism at the systems level. GSMs consist of hundreds or thousands of reactions. They have thus largely been analyzed with computationally efficient constraint-based methods such as...

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PMID: 31748914
DOI: 10.1007/s00018-019-03383-z
PMCID: PMC11104862

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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