Article

In situ profiling of nanoscale displacements uncovers mechano-architectural predictors of osteoarthritis emergence

2025-12-08

Abstract excerpt

Mechanical and anatomical interplay between the distinct tissues of the knee joint is essential for maintaining functional integrity during healthy ageing and contributes to the mechanisms that drive osteoarthritis (OA). In this study, we investigate how age- and disease-associated alterations in joint anatomy influence load transmission and tissue-level strain distribution. Using full-field synchrotron X-ray comp...

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Literature Corpus work: 097409b9-d1c1-59f6-a93c-45a842d733dd
DOI: 10.64898/2025.12.04.692296

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