Article

Computational and Imaging Approaches for Precision Characterization of Bone, Cartilage, and Synovial Biomolecules

2025-06-09

Abstract excerpt

<h4>Background: </h4> /Objectives: Degenerative joint diseases (DJDs) involve intricate molecular disruptions within bone, cartilage, and synovial tissues—often preceding overt radiographic changes. These tissues exhibit complex biomolecular architectures, and their degeneration leads to microstructural disorganization and inflammation that are challenging to detect with conventional imaging. This review aims to s...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8767836c-2215-5bc9-9fca-8c5011f8061a
DOI: 10.20944/preprints202506.0706.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Computational and Imaging Approaches for Precision Characterization of Bone, Cartilage, and Synovial BiomoleculesDOI 10.20944/preprints202506.0706.v1Read

Biomarker-Guided Imaging and AI-Augmented Diagnosis of Degenerative Joint DiseaseSemantic proximity Read

Emerging Diagnostic Approaches for Musculoskeletal Disorders: Advances in Imaging, Biomarkers, and Clinical AssessmentSemantic proximity Read

Deep learning for large scale MRI-based morphological phenotyping of osteoarthritis.Semantic proximity Read

Spatial analysis of the osteoarthritis microenvironment: techniques, insights, and applications.Semantic proximity Read

Osteoarthritis phenotypes: advancing precision medicine through clinical, structural, and molecular stratification.Semantic proximity Read

Personalized Risk Model and Leveraging of Magnetic Resonance Imaging-Based Structural Phenotypes and Clinical Factors to Predict Incidence of Radiographic Osteoarthritis.Semantic proximity Read

Automatic framework for evaluating osteoarthritic cartilage severity: high-resolution cartilage thickness mapping and scoringSemantic proximity Read

Structural phenotypes of osteoarthritis are clinically and genetically distinct: findings from 59,539 UK Biobank participantsSemantic proximity Read

Editorial Commentary: Traveling to A New Dimension in Anterior Cruciate Ligament Injury Risk Stratification: Holistic 3-Dimensional Knee Phenotyping via Automated Artificial Intelligence Pipelines.Semantic proximity Read

Emerging AI and Biomarker–Driven Precision Medicine in Autoimmune Rheumatic Diseases: From Diagnostics to Therapeutic Decision-MakingSemantic proximity Read

[Biomarkers and imaging for diagnosis and stratification of rheumatoid arthritis and spondylarthritis in the BMBF consortium ArthroMark].Semantic proximity Read

MRI and biomechanics multidimensional data analysis reveals R2 -R1ρ as an early predictor of cartilage lesion progression in knee osteoarthritis.Semantic proximity Read