Article

Membrane-associated periodic skeleton regulates major forms of endocytosis in neurons through a signaling-driven positive feedback loop

2025-12-15

Abstract excerpt

Endocytosis is an evolutionarily conserved process that enables neurons to internalize signaling receptors and membrane proteins, maintaining cellular homeostasis and supporting rapid responses to extracellular cues. The neuronal membrane-associated periodic skeleton (MPS), a lattice-like cytoskeletal structure composed of actin and spectrin, has been shown to restrict clathrin-mediated endocytosis (CME) at the ax...

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Literature Corpus work: 09552bd7-3110-508b-9d77-f13580d8d335
DOI: 10.64898/2025.12.12.693977

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