Article

A multi-faceted analysis of synapses reveals the role of neuroligin-1 cleavage in presynaptic vesicle accumulation in the lateral amygdala

2023-11-07

Abstract excerpt

Neuroligin-1 (NLGN1) is a cell adhesion molecule found at excitatory glutamatergic synapses in the brain which regulates synaptic function and maturation. Extracellular cleavage of NLGN1 by proteases has been shown to control vesicle release in cultured neurons, but nothing is known about the underlying changes to synapse structure that accompany this, or how synapse function is affected in brain tissue. We found...

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Literature Corpus work: 2aed6e5c-6cf8-51ea-b0c1-1547c2a3d03e
DOI: 10.1101/2023.11.07.566075

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