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A panel sequencing dataset of peripheral blood gene variations in pan-cancer.

Scientific data - 20 Jul 2024

Liu Yanxia, Liu Jie, Zhang Shouwei, Wang Jinyue, Sun Zhihong, Sun Huaibo, Yang Ying, Zheng Guangmin, Huang Yu, Li Meng, Zhang Zhaojun, Xiao Jingfa, Zeng Changqing, Sun Chengming, Qu Hongzhu, Fang Xiangdong

Abstract excerpt

Circulating cell-free DNA (cfDNA) in the peripheral blood is a promising biomarker for cancer diagnosis and prognosis. Somatic mutations identified in cancers have been used to detect therapeutic targets for clinical transformation and individualize drug selection, while germline variants can predict a patient's risk of developing cancer and drug sensitivity. However, no platform has been developed to analyze,...

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Identifiers

PMID: 39033182
DOI: 10.1038/s41597-024-03620-6
PMCID: PMC11271301

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