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Article

Causal relationship between genetically determined plasma metabolites and stroke: A two sample Mendelian randomization study.

Progress in neuro-psychopharmacology & biological psychiatry - 20 Dec 2024

Huang Yi, Chen Siqi, Zhang Enhao, Han Liyuan

Abstract excerpt

INTRODUCTION: This study investigates the causal relationship between plasma metabolites and stroke. METHOD: The primary analytical approach employed was the inverse variance weighted (IVW) method, complemented by the weighted median (WM) and MR Egger methods for Additionally, validation of the identified plasma metabolites was performed using the Steiger test and LD linkage disequilibrium score. Furthermore, the...

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Mendelian Randomization Analysis
Polymorphism, Single Nucleotide
Stroke

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39222903
DOI: 10.1016/j.pnpbp.2024.111133

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