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Article

Human blood metabolites and lacunar stroke: A Mendelian randomization study.

International journal of stroke : official journal of the International Stroke Society - 1 Jan 2023

Guo Meng-Nan, Hao Xiao-Yan, Tian Jie, Wang Yun-Chao, Li Jia-Di, Fan Yu, Shi Jing-Jing, Ma Dong-Rui, Li Shuang-Jie, Zuo Chun-Yan, Liang Yuan-Yuan, Li Meng-Jie, Shen Si, Liu Fen, Yao Da-Bao, Xu Yu-Ming, Shi Chang-He

Abstract excerpt

BACKGROUND: Lacunar stroke accounts for a quarter of all strokes, but little is known about the underlying pathological mechanisms. Analysis of serum metabolites may allow better understanding of the underlying biological processes. Mendelian randomization (MR) can provide information on the causality of associations. AIMS: To identify causal relationships between serum metabolites and lacunar stroke. METHODS: We...

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PMID: 36367219
DOI: 10.1177/17474930221140792

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