Article

Metabolome and transcriptome analysis of oral mucosa of HIV+ patients reveal a role for polyamine metabolic pathway in T cell dysfunction

2022-05-09

Abstract excerpt

<title>Abstract</title> Metabolic changes of immune cells contribute to both physiological and pathophysiological outcomes of immune reactions. How viruses alter the metabolic states of mucosal T cells and the precise mechanisms underlying the persisting immune dysfunction during chronic viral infections are key questions that have not been fully addressed. Here, by comparing transcriptome and salivary metabol...

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Literature Corpus work: bddc702d-99d3-51f2-b540-39ceb70710f3
DOI: 10.21203/rs.3.rs-1595110/v1

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