Article

Autophagy-Mediated Clearance of Free Genomic DNA in the Cytoplasm Promoted the Growth and Survival of Breast Cancer Cells

2021-02-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: The cGAS (GMP-AMP synthase)-triggered senescence-associated secretory phenotype (SASP) in promotion of cancer progression has been extensively documented. However, the role of cGAS-mediated DNA autophagy is little evaluated in breast cancer cells.<bold>Methods</bold>: Immunofluorescence, senescence associated-β-galactosidase staining (SA-β-gal) and Western blot...

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Literature Corpus work: 090d0ee5-edaa-5a6e-8751-5f78b2fe9244
DOI: 10.21203/rs.3.rs-227734/v1

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