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Autophagy Roles in the Modulation of DNA Repair Pathways

7 Nov 2017

Abstract excerpt

Autophagy and DNA repair are biological processes vital for cellular homeostasis maintenance and when dysfunctional, they lead to several human disorders including premature aging, neurodegenerative diseases, and cancer. The interchange between these pathways is complex and it may occur in both directions. Autophagy is activated in response to several DNA lesions types and it can regulate different mechanisms and...

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PMID: 29112132
DOI: 10.3390/ijms18112351

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