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Autophagy role(s) in response to oncogenes and DNA replication stress

13 Aug 2019

Abstract excerpt

Autophagy is an evolutionarily conserved process that captures aberrant intracellular proteins and/or damaged organelles for delivery to lysosomes, with implications for cellular and organismal homeostasis, aging and diverse pathologies, including cancer. During cancer development, autophagy may play both tumour-supporting and tumour-suppressing roles. Any relationships of autophagy to the established...

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PMID: 31409894
DOI: 10.1038/s41418-019-0403-9

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