Article

T-2 Toxin Induces Oxidative Stress at Low Doses Via ATF3∆Zip2a/2b-Mediated Ubiquitination and Degradation of Nrf2

2021-05-13

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>T-2 toxin is mainly produced by <italic>Fusarium</italic> species, which is an extremely toxic mycotoxin to humans and animals. It is well known that T-2 toxin induces oxidative stress, but the molecular mechanism is still unknown. <bold>Results: </bold>In this study, we found that T-2 toxin significantly promoted ROS accumulation in MCF-7 cells at low doses whi...

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Literature Corpus work: 08f840dd-e83c-57c8-a847-a5af0230ddf4
DOI: 10.21203/rs.3.rs-506960/v1

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