Article

Estimating Drivers of Cell State Transitions Using Gene Regulatory Network Models

2016-11-21

Abstract excerpt

Specific cellular states are often associated with distinct gene expression patterns. These states are plastic, changing during development, or in the transition from health to disease. One relatively simple extension of this concept is to recognize that we can classify different cell-types by their active gene regulatory networks and that, consequently, transitions between cellular states can be modeled by change...

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Literature Corpus work: 8a263630-855e-52ac-ad69-faf78aea072f
DOI: 10.1101/089003

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