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PDZ and LIM Domain-Encoding Genes: Molecular Interactions and their Role in Development

1 Jan 2007

Abstract excerpt

PDZ/LIM genes encode a group of proteins that play very important, but diverse, biological roles. They have been implicated in numerous vital processes, e.g., cytoskeleton organization, neuronal signaling, cell lineage specification, organ development, and oncogenesis. In mammals, there are ten genes that encode for both a PDZ domain, and one or several LIM domains: four genes of the ALP subfamily (ALP, Elfin,...

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Identifiers

PMID: 17767364
DOI: 10.1100/tsw.2007.232

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