Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic determinants of syndactyly: perspectives on pathogenesis and diagnosis

12 May 2022

Abstract excerpt

The formation of the digits is a tightly regulated process. During embryogenesis, disturbance of genetic pathways in limb development could result in syndactyly; a common congenital malformation consisting of webbing in adjacent digits. Currently, there is a paucity of knowledge regarding the exact developmental mechanism leading to this condition. The best studied canonical interactions of Wingless-type-Bone...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital limb and hand anomalies
Share to Dupuytren's Contracture and Treatments
Share to Hedgehog Signaling Pathway Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35549993
DOI: 10.1186/s13023-022-02339-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic determinants of syndactyly: perspectives on pathogenesis and diagnosisPMID 35549993Read ↗

Syndactyly: phenotypes, genetics and current classification.Semantic proximity Read ↗

Polydactyly: phenotypes, genetics and classification.Semantic proximity Read ↗

Genetics of Limb Development and Congenital Hand MalformationsSemantic proximity Read ↗

Genetic Syndromes Associated With Congenital Upper Limb Differences.Semantic proximity Read ↗

Genetic Overview of Syndactyly and PolydactylySemantic proximity Read ↗

Clinical, genetic, and molecular aspects of split-hand/foot malformation: an update.Semantic proximity Read ↗

Polydactyly: Clinical and molecular manifestationsSemantic proximity Read ↗

[Brachydactyly and the molecular mechanisms of digit formation].Semantic proximity Read ↗

Polydactyly: how many disorders and how many genes? 2010 update.Semantic proximity Read ↗

Molecular‐pathogenetic classification of genetic disorders of the skeletonSemantic proximity Read ↗

Humeroradial Synostosis: An Updated Classification and Differential Diagnosis Based on Genetic Aetiology.Semantic proximity Read ↗

Distal limb malformations: underlying mechanisms and clinical associations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.