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Molecular Profiling of Primary versus Paired Asynchronous Metastatic Clear Cell Renal Cell Carcinoma Reveals Heterogeneity in Tumor Immune Microenvironment

2025-09-25

Abstract excerpt

<title>Abstract</title> <p> Background and Objective: The tumor immune microenvironment (TIME) shows significant heterogeneity in primary clear cell renal cell carcinoma (ccRCC). As TIME heterogeneity between primary and paired metastatic tumors of ccRCC is less understood, we characterize and compare the TIME of primary ccRCC with paired asynchronous metastases. Methods We analyzed patients who developed ccRCC...

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Literature Corpus work
0872b3dd-0b66-5fef-9f6f-40a268617a65
DOI
10.21203/rs.3.rs-7087297/v1
Open publication

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Molecular Profiling of Primary versus Paired Asynchronous Metastatic Clear Cell Renal Cell Carcinoma Reveals Heterogeneity in Tumor Immune MicroenvironmentDOI 10.21203/rs.3.rs-7087297/v1
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