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Genome-wide cross-trait analysis of vascular dementia and Alzheimer’s disease highlights novel loci and lung-brain axis

2026-03-13

Abstract excerpt

<title>Abstract</title> <p> Until now, most genetic risk for vascular dementia (VD) remains unknown. Here, we firstly performed the largest cross-ancestry genome-wide association study meta-analysis comprising 5,886 VD and 1,027,883 controls of European, East Asian, South Asian, African, and Admixed American ancestry. We identified 37 genome-wide significant loci including <italic>CLU</italic> and <italic>APO...

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Literature Corpus work
082f40dc-32e2-5beb-bbe4-a8609be02899
DOI
10.21203/rs.3.rs-8988189/v1
Open publication

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Genome-wide cross-trait analysis of vascular dementia and Alzheimer’s disease highlights novel loci and lung-brain axisDOI 10.21203/rs.3.rs-8988189/v1
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