Article
A genome-wide association meta-analysis of all-cause and vascular dementia.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Sept 2024
Abstract excerpt
INTRODUCTION: Dementia is a multifactorial disease with Alzheimer's disease (AD) and vascular dementia (VaD) pathologies making the largest contributions. Yet, most genome-wide association studies (GWAS) focus on AD. METHODS: We conducted a GWAS of all-cause dementia (ACD) and examined the genetic overlap with VaD. Our dataset includes 800,597 individuals, with 46,902 and 8702 cases of ACD and VaD, respectively....
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