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Article

Genetic Determinants of Vascular Dementia.

The Canadian journal of cardiology - 1 Aug 2024

Pathan Nazia, Kharod Muskaan Kaur, Nawab Sajjha, Di Scipio Matteo, Paré Guillaume, Chong Michael

Abstract excerpt

Vascular dementia (VaD) is a prevalent form of cognitive impairment with underlying vascular etiology. In this review, we examine recent genetic advancements in our understanding of VaD, encompassing a range of methodologies including genome-wide association studies, polygenic risk scores, heritability estimates, and family studies for monogenic disorders revealing the complex and heterogeneous nature of the...

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Identifiers

PMID: 38579965
DOI: 10.1016/j.cjca.2024.03.025

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