Article

Ethnicity-Specific Molecular Alterations in MAPK and JAK/STAT Pathways in Early-Onset Colorectal Cancer

2025-02-23

Abstract excerpt

<h4>Background/Objectives</h4> Early-onset colorectal cancer (EOCRC), defined as colorectal cancer (CRC) diagnosed before the age of 50, has been increasing in incidence, particularly among Hispanic/Latino (H/L) populations. Despite this trend, the underlying molecular mechanisms driving EOCRC disparities remain poorly understood. The MAPK and JAK/STAT pathways play critical roles in tumor progression, proliferat...

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Literature Corpus work: 081279e5-9446-52ab-b785-567bd432c645
DOI: 10.1101/2025.02.17.25322443

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