Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ethnicity-Specific Molecular Alterations in MAPK and JAK/STAT Pathways in Early-Onset Colorectal Cancer

25 Mar 2025

Abstract excerpt

Background/Objectives: Early-onset colorectal cancer (EOCRC), defined as colorectal cancer (CRC) diagnosed before the age of 50, has been increasing in incidence, particularly among Hispanic/Latino (H/L) populations. Despite this trend, the underlying molecular mechanisms driving EOCRC disparities remain poorly understood. The MAPK and JAK/STAT pathways play critical roles in tumor progression, proliferation, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Cancer Treatments and Studies
Share to Cytokine Signaling Pathways and Interactions
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40227607
DOI: 10.3390/cancers17071093

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ethnicity-Specific Molecular Alterations in MAPK and JAK/STAT Pathways in Early-Onset Colorectal CancerPMID 40227607Read ↗

Ethnicity-Specific Molecular Alterations in MAPK and JAK/STAT Pathways in Early-Onset Colorectal CancerSemantic proximity Read ↗

Molecular Heterogeneity in Early-Onset Colorectal Cancer: Pathway-Specific Insights in High-Risk PopulationsSemantic proximity Read ↗

Molecular Heterogeneity in Early-Onset Colorectal Cancer: Pathway-Specific Insights in High-Risk PopulationsSemantic proximity Read ↗

Detecting PI3K and TP53 Pathway Disruptions in Early-Onset Colorectal Cancer Among Hispanic/Latino PatientsSemantic proximity Read ↗

Mutational and co-mutational landscape of early onset colorectal cancer.Semantic proximity Read ↗

Racial/Ethnic and Sex Differences in Somatic Cancer Gene Mutations among Patients with Early-Onset Colorectal Cancer.Semantic proximity Read ↗

Clinical Rather Than Genetic Factors Drive Prognosis in Early- Onset Colorectal Cancer: A Retrospective Cohort StudySemantic proximity Read ↗

Transcriptomic landscape of early age onset of colorectal cancer identifies novel genes and pathways in Indian CRC patientsSemantic proximity Read ↗

Conversational Artificial Intelligence-Based Integration of Clinical and Genomic Data Identifies MAPK Alterations in Colorectal CancerSemantic proximity Read ↗

Early-Onset Colorectal Cancer: From Genetic Discovery to Clinical InnovationSemantic proximity Read ↗

Integrating Artificial Intelligence and Precision Medicine to Characterize JAK-STAT Pathway Alterations in FOLFOX-Treated Colorectal Cancer in Disproportionately Affected GroupsSemantic proximity Read ↗

Unveiling prognostic value of JAK/STAT signaling pathway related genes in colorectal cancer: a study of Mendelian randomization analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.