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Early-Onset Colorectal Cancer: From Genetic Discovery to Clinical Innovation

1 Jun 2025

Abstract excerpt

The rising incidence of early-onset colorectal cancer (EOCRC) presents a growing challenge to traditional approaches in screening, treatment, and survivorship. EOCRC is increasingly recognized as a biologically distinct entity, driven by complex inter-related biological, genetic, behavioral, and socioenvironmental factors. This chapter reviews the molecular and clinical features that distinguish EOCRC, with...

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PMID: 40638868
DOI: 10.1200/edbk-25-473618

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