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Article

MxA inhibits hepatitis B virus replication by interaction with hepatitis B core antigen

23 Jan 2012

Abstract excerpt

UNLABELLED: Human MxA, an interferon-inducible cytoplasmic dynamin-like GTPase, possesses antiviral activity against multiple RNA viruses. Recently, MxA has also been demonstrated to have activity against the hepatitis B virus (HBV), a well-known DNA virus responsible for acute and chronic liver disease in humans. We investigated the molecular mechanism for the anti-HBV activity of MxA. Our results demonstrated...

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PMID: 22271421
DOI: 10.1002/hep.25608

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