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The anti-viral dynamin family member MxB participates in mitochondrial integrity

26 Feb 2020

Abstract excerpt

The membrane deforming dynamin family members MxA and MxB are large GTPases that convey resistance to a variety of infectious viruses. During viral infection, Mx proteins are known to show markedly increased expression via an interferon-responsive promoter to associate with nuclear pores. In this study we report that MxB is an inner mitochondrial membrane GTPase that plays an important role in the morphology and...

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PMID: 32102993
DOI: 10.1038/s41467-020-14727-w

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