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Article

Human MxB Protein Is a Pan-herpesvirus Restriction Factor.

Journal of virology - 1 Sept 2018

Schilling Mirjam, Bulli Lorenzo, Weigang Sebastian, Graf Laura, Naumann Sebastian, Patzina Corinna, Wagner Valentina, Bauersfeld Liane, Goujon Caroline, Hengel Hartmut, Halenius Anne, Ruzsics Zsolt, Schaller Torsten, Kochs Georg

Abstract excerpt

Herpesvirus infections are highly prevalent in the human population and persist for life. They are often acquired subclinically but potentially progress to life-threatening diseases in immunocompromised individuals. The interferon system is indispensable for the control of herpesviral replication. However, the responsible antiviral effector mechanisms are not well characterized. The type I interferon-induced,...

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Identifiers

PMID: 29950411
DOI: 10.1128/JVI.01056-18
PMCID: PMC6096802

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