Article

Computational pipeline for the PGV-001 neoantigen vaccine trial

2017-08-10

Abstract excerpt

This paper describes the sequencing protocol and computational pipeline for the PGV-001 personalized vaccine trial. PGV-001 is a therapeutic peptide vaccine targeting neoantigens identified from patient tumor samples. Peptides are selected by a computational pipeline which identifies mutations from tumor/normal exome sequencing and ranks mutant sequences by a combination of predicted Class I MHC affinity and abund...

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Literature Corpus work: 07b56b18-8ce8-5efd-855d-13cd5ae34a97
DOI: 10.1101/174516

Open publication

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