Article

LENS: Landscape of Effective Neoantigens Software

2022-04-05

Abstract excerpt

<h4>Motivation</h4> Elimination of cancer cells by T cells is a critical mechanism of anti-tumor immunity and cancer immunotherapy response. T cells recognize cancer cells by engagement of T cell receptors with peptide epitopes presented by major histocompatibility complex (MHC) molecules on the cancer cell surface. Peptide epitopes can be derived from antigen proteins coded for by multiple genomic sources. Bioin...

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Literature Corpus work: 9ddb13f0-1c97-536d-b99c-f6fc3df45b20
DOI: 10.1101/2022.04.01.486738

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