Article

ProTECT – Prediction of T-cell Epitopes for Cancer Therapy

2019-07-09

Abstract excerpt

Somatic mutations in cancers affecting protein coding genes can give rise to potentially therapeutic neoepitopes. These neoepitopes can guide Adoptive Cell Therapies (ACTs) and Peptide Vaccines (PVs) to selectively target tumor cells using autologous patient cytotoxic T-cells. Currently, researchers have to independently align their data, call somatic mutations and haplotype the patient’s HLA to use existing neoep...

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Literature Corpus work: 73dd1d51-db3e-5e1f-a2f1-e3300cc8a755
DOI: 10.1101/696526

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