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Integrative biomarker discovery and immune profiling for ulcerative colitis: a multi-methodological approach

16 Oct 2024

Abstract excerpt

Background We aimed to pinpoint biomarkers, create a diagnostic model for ulcerative colitis (UC), and delve into its immune features to better understand this autoimmune condition. Methods The sequencing data for both the UC and the control groups were obtained from GEO, including both bulk and single-cell data. Using GSE87466 as training group, we applied differential analysis, WGCNA, PPI, LASSO, RF, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39414957
DOI: 10.1038/s41598-024-75797-0

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