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Novel Nonsense Variants c.58C>T (p.Q20X) and c.256G>T (p.E85X) in the CHEK2 Gene Identified in Breast Cancer Patients from Balochistan.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2016

Baloch Abdul Hameed, Khosa Ahmad Nawaz, Bangulzai Nasrullah, Shuja Jamila, Naseeb Hafiz Khush, Jan Mohammad, Marghazani Illahi Bakhsh, Kakar MasoodulHaq, Baloch Dost Mohammad, Cheema Abdul Majeed, Ahmad Jamil

Abstract excerpt

Breast cancer is very common and the leading cause of cancer deaths among women globally. Hereditary cases account for 510% of the total burden and CHEK2, which plays crucial role in response to DNA damage to promote cell cycle arrest and repair or induce apoptosis, is considered as a moderate penetrance breast cancer risk gene. Our objective in the current study was to analyze mutations in related to breast...

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PMID: 27510020

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CHEK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Novel Nonsense Variants c.58C>T (p.Q20X) and c.256G>T (p.E85X) in the CHEK2 Gene Identified in Breast Cancer Patients from Balochistan.PMID 27510020Read ↗

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