Article
Plasma-based organ-specific aging and mortality models unveil diseases as accelerated aging of organismal systems
2024-04-10
Abstract excerpt
Aging is a complex process manifesting at the molecular, cell, organ and organismal levels. It leads to functional decline, disease and ultimately death, but the relationship between these fundamental biomedical features remains elusive. By applying machine learning to plasma proteome data of over fifty thousand human subjects in the UK Biobank and other cohorts, we report organ-specific and conventional aging mod...
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Identifiers and source
- Literature Corpus work
- fea665af-dd27-5554-b430-54e20c769344
- DOI
- 10.1101/2024.04.08.24305469