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Large-scale genetic investigation reveals genetic liability to multiple complex traits influencing a higher risk of ADHD.

Scientific reports - 19 Nov 2021

García-Marín Luis M, Campos Adrián I, Cuéllar-Partida Gabriel, Medland Sarah E, Kollins Scott H, Rentería Miguel E

Abstract excerpt

Attention Deficit-Hyperactivity Disorder (ADHD) is a complex psychiatric and neurodevelopmental disorder that develops during childhood and spans into adulthood. ADHD's aetiology is complex, and evidence about its cause and risk factors is limited. We leveraged genetic data from genome-wide association studies (GWAS) and performed latent causal variable analyses using a hypothesis-free approach to infer causal...

Topics

Attention Deficit Disorder with Hyperactivity
Child
Databases, Factual
Genetic Association Studies
Genetic Linkage
Genetic Predisposition to Disease
Genetic Variation
Genome-Wide Association Study
Genomics
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multifactorial Inheritance

Obesity

Phenotype

Risk

Substance-Related Disorders

Source

Open in PubMed Open full text

Identifiers

PMID: 34799595
DOI: 10.1038/s41598-021-01517-7
PMCID: PMC8604995

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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