Article

Integrative multi-Omics analysis depicts the methylome and hydroxymethylome of recurrent bladder cancers and identifies biomarkers for predicting PD-L1 expression

2023-01-13

Abstract excerpt

<h4>Background: </h4> Urinary bladder cancer is one of the most common malignancies of the urinary tract; however, the mechanism of its high recurrence and responses to immunotherapy remains unclear, resulting in difficulties in clinical outcome prediction. Epigenetic alterations, especially DNA methylation, play important roles in bladder cancer development and are increasingly investigated as biomarkers for diag...

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Literature Corpus work: 07454aef-55db-5074-bce3-575edd35a1b8
DOI: 10.21203/rs.3.rs-2456805/v1

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